Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydorchloride (Cas No. 137-09-7),... Technical Report Series... No.401... U.S. DHHS... 1995.

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ContributionsNational Cancer Institute (U.S.)
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Open LibraryOL18123454M

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NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CASRN ) in F/N Rats and B6C3F1 Mice (Gavage Studies) Rats: F/N; Mice: B6C3F1 Carcinogenesis Results.

Toxicology and carcinogenesis studies of 2,4-diaminophenol dihydrochloride (CAS no. ) in F/N rats and B6C3F₁ mice (gavage studies) 2,4-diaminophenol dihydrochloride (gavage studies) Responsibility: National Toxicology Program.

2,4-Diaminophenol dihydrochloride: Target Organs and Levels of Evidence for TR NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CASRN ) in F/N Rats and B6C3F1 Mice (Gavage Studies).

Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of 2,4-diaminophenol dihydrochloride (cas no. ): in F/N rats and B6C3F₁ mice (gavage studies).

[National Toxicology Program (U.S.);]. 2,4-Diaminophenol dihydrochloride is used in the manufacture of dyes and as a color accelerator in photographic developers. Toxicology and carcinogenesis studies were conducted by administering 2,4-diaminophenol dihydrochloride (greater than 97% pure) in corn oil by gavage to F/N rats and B6C3F1 mice for 16 days, 13 weeks, and 2 : National Toxicology Program.

Author(s): National Toxicology Program (U.S.) Title(s): NTP technical report on the toxicology and carcinogenesis studies of 2,4-diaminophenol dihydrochloride (cas no): in F/N rats and B6C3F₁ mice (gavage studies)/ National Toxicology Program.

NTP technical report on the toxicology and carcinogenesis studies of 2,4-diaminophenol dihydrochloride (CAS no. ) in F/N rats and B6C3F₁ mice (gavage studies) Published: () NTP technical report on the toxicology and carcinogenesis studies of nickel sulfate hexahydrate (CAS Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydorchloride book.

) in F/N rats and B6C3F₁ mice. Abstract 2,4-Diaminophenol dihydrochloride is used in the manufacture of dyes and as a color accelerator in photographic developers.

Toxicology and carcinogenesis studies were conducted by administering 2,4-diaminophenol dihydrochloride (greater than 97% pure) in corn oil by gavage to F/N rats and B6C3F1 mice for 16 days, 13 weeks, and 2 years. 2,4-Diaminophenol | C6H8N2O | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities.

Toxicology & Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride in F/N Rats and B6C3F1 Mice (Gavage Studies). Technical Report Series No. () NIH Publication No. U.S. Department of Health and Human Services, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC introduced the the toxicology and carcinogenesis studies of 2,4-diaminophenol dihydrochloride by discussing the uses and rationale for study, describing the experimental design, reporting on survival and body weight effects, and comnenting on compound-related neoplastic and non-neoplastic lesions in.

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,4-Diaminophenol Dihydrochloride (CAS NO. ) in F/N Rats and B6C3F1 Mice (Gavage Studies). Natl. Toxicol. Program Tech. Rep. Ser., (). 2,4-Diaminophenoxyethanol dihydrochloride / sulfate is used as an ingredient of oxidative hair colouring products at a maximum final (on-head) concentration of %, after mixing the hair dye formulation with a hydrogen peroxide preparation typically in proportions.

Principles of Carcinogenesis 2. DNA Reactive and Non- DNA Reactive Carcinogens 3. Methods for Screening for Carcinogenicity 4. Model of Carcinogenesis Incorporating DNA Damage and Increased Cell Proliferation 5. Mode of Action Analysis and Extrapolation of In Vitro and Animal Studies to Humans.

NTP technical report on the toxicology and carcinogenesis studies of nickel oxide (CAS no. ) in NTP technical report on the carcinogenesis studies of 4,4'-methylenedianiline dihydrochloride (CAS no. 1 NTP technical report on the carcinogenesis bioassay of 1,2-dibromochloropropane (CAS no.

) in. 2,4-Diaminophenol dihydrochloride Gav MR-NE 2 (2) 0 2 (6)Diethanolamine Derm FR-NE 0 0 0 03,4-Dihydro coumarin Gav MR-SE 0 (2) 2 (2) 0 (6) 4 (12)*3,3′-Dimethyl benzidine dihydrochloride e DW MR-NE 0 0 0 0. NATIONAL TOXICOLOGY PROGRAM Technical Report Series No.

TOXICOLOGY AND CARCINOGENESIS. STUDIES OF. TRIS(2-ETHYLHEXYL)PHOSPHATE (CASNO. ) IN F/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S.

DEPARTMENT OF HEALTH AND HUMAN SERVICES. Public Health Service National Institutes. Health. Toxicology and carcinogenesis studies were conducted by administering acetaminophen (purity >99%) in feed to groups of F/N rats and B6C3F1 mice of each sex for 14 days, 13 weeks, and 2 years.

Genetic toxicology studies were conducted in Salmonella typhimurium and Chinese hamster ovary cells. DAY STUDIES: Rats were fed diets containing 0. Studies in volunteers in which HC Blue No. 2 at use concentrations was applied to the scalp, Toxicology Program oral feeding bioassays in rats and mice shows the ingredient to be relatively nontoxic.

National Toxicology Programme. Toxicology and Carcinogenesis studies of 2,4-diaminophenol. dihydrochloride (CAS ) in F rats and B6C3F1 mice (gavage studies). NTP Technical report No TR US DHSS, NIH Google Scholar. (). Toxicology and Carcinogenesis of Various Chemicals Used in the Preparation of Vaccines.

Clinical Toxicology: Vol. 4, No. 2, pp. Hence, whether Jin et al. (a) were unaware of or thought findings from chronic studies in rodents not directly relevant to their 2,4,6-TCP aquatic impact studies, the purpose of this communication is to make better known the 2-year toxicology and carcinogenesis bioassays of 2,4,6-trichlorophenol in Fischer rats and B6C3F1 mice.

The following investigators are involved in Toxicology/Carcinogenesis projects: Gregg Dinse, Grace Kissling, Keith Shockley. Examples of three general areas of research and various special topics are given below: Rodent Cancer Bioassays. Improved statistical analysis of tumor data; Incorporation and analysis of historical control data.

Toxicology and carcinogenesis studies of dietary titanium dioxide‐coated mica in male and female Fischer rats. Journal of Toxicology and Environmental Health: Vol. 28, No. 4, pp. quired guideline studies, mode-of-action studies, behavioral and func-tional assessments, and predictive assays/models.

Test guideline-driven study designs covering these periods have evolved over time and are subject to additions or variations, depending on what is known about the tested compound.

In addition, the field of toxicology is pushing. Carcinogenesis studies of 4,4′-Methylenedianiline Dihydrochloride in F/N Rats and B6C3F1 Mice (Drinking Water Studies) February Journal of Toxicology and Environmental Health 18(3) Toxicology and carcinogenesis studies of methacrylonitrile (CAS No.

) in F/N rats and B6C3F1 mice (gavage studies). [No authors listed] Methacrylonitrile is an unsaturated aliphatic nitrile. It is widely used in the preparation of homopolymers and copolymers, elastomers, and plastics and as a chemical intermediate in the preparation.

NTP technical report on the toxicology and carcinogenesis studies of 3,3'-dimethoxybenzidine dihydrochloride (CAS no. ) in F/N rats (drinking water studies) by Morgan, D; National Toxicology Program (U.S.).

An illustration of an open book. Books. An illustration of two cells of a film strip. Video. An illustration of an audio speaker. Audio An illustration of a " floppy disk. Full text of "NTP technical report on the toxicology and carcinogenesis studies of nitrofurantoin (CAS no.

Wexler, in Encyclopedia of Toxicology (Third Edition), Chemical Specific Factual Databanks Chemical Carcinogenesis Research Information System. Chemical Carcinogenesis Research Information System (CCRIS) is a scientifically evaluated and fully referenced data bank, developed by the National Cancer Institute (NCI), but no longer updated.

It contains over chemical records with. Toxicology and carcinogenesis studies of hydrochlorothiazide, a benzothiadiazide diuretic, were conducted by administering diets containing the drug to both sexes of F rats and B6C3F1 mice in day, week and 2-year studies.

No rats died during the day or week studies at dietary concentrations of up to 50, ppm. National Toxicology Program technical report series Toxicology and carcinogenesis studies of 2,3',4,4',5-pentachlorobiphenyl (PCB ) (CAS No.

) in female harlan Sprague-Dawley rats (gavage studies). PMID Toxicology and carcinogenesis studies of ethylbenzene (CAS NO. ) in F/N rats and B6C3F1 mice (inhalation studies) Author(s) National Toxicology Program:: NTP Year. Journal. National Toxicology Program Technical Report Series ISSN: Publisher.

U.S. Department of Health and Human Services, National Institutes of Health. Toxicology and carcinogenesis studies of 3,3'-dimethylbenzidine dihydrochloride CAS no. ) in F/N rats (drinking water studies) 3,3'-dimethylbenzidine dihydrochloride, NTP TR 3,3'-dimethylbenzidine dihydrochloride (drinking water studies) Responsibility: National Toxicology.

Toxicology and carcinogenesis studies were conducted by administering ochratoxin A (98% pure) in corn oil by gavage to groups of F/N rats of each sex for 16 days, 13 weeks, 9 months, 15 months, or 2 years.

Only rats were studied because ochratoxin A has been shown to be carcinogenic in mice. Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of 3,3'-dimethoxybenzidine dihydrochloride (CAS no.

) in F/N rats (drinking water studies). [D Morgan; National Toxicology Program (U.S.)]. (). Toxicology and carcinogenesis studies of dietary titanium dioxide‐coated mica in male and female Fischer rats. Journal of Toxicology and Environmental Health: Vol.

29, No. 4. Get this from a library. NTP technical report on the carcinogenesis studies of 4,4'-methylenedianiline dihydrochloride: (CAS no. ) in F/N rats and B6C3F₁ mice (drinking water studies).

[National Toxicology Program (U.S.);]. In the broadest possible sense, carcinogenesis is a process of generation of benign and malignant neoplasm. Agents such as viruses, radiation, and chemicals are able to induce cancer in humans and experimental animals.

However, the importance of chemicals as a cause of cancer has long been recognized in basic and clinical studies, and is emphasized by the epidemic of tobacco-related lung. Three N-acetylated metabolites (N-acetyl-1,3-diaminobenzene, N,N'-diacetyl-2,4-diaminophenol and N,N'-diacetyl-1,3-diaminobenzene) accounted for 49 and 37% of the urinary excretion of group 2 and.

Full text of "NTP technical report on the toxicology and carcinogenesis studies of chlorinated water (CAS NOS. and ) and chloraminated water (CAS NO. ) (deionized and charcoal-filtered) in F/N rats and B6C3F1 mice (drinking water studies)" See other formats.These studies are designed and conducted to characterize and evaluate the toxicologic potential, including carcinogenic activity, of selected chemicals in laboratory animals (usually two species, rats and mice).

Chemicals selected for NTP toxicology and carcinogenesis studies .Toxicology and carcinogenesis studies were conducted by administering benzofuran (approximately 99% pure) in corn oil by gavage to groups of F/N rats and B6C3F1 mice of each sex for 14 days, 13 weeks, or 2 years. Genetic toxicology tests were conducted in Salmonella typhimurium, mouse lymphoma cells, and Chinese hamster ovary (CHO) cells.

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